Microdosing shrooms?

I suffer from consant dissociation, anxiety and maybe a bit of depression. I have microdosed before and worked from what I remember, however im wondering now since people always pressure how important set and setting is, if your taking psylocybin to mental health issues doesn’t that pretty much automatically mean your set is bad? So should i take them and how much, im also on 10mg of lexapro and btw the strain is called amazonia.